Tablet Productions: Its Solution and Problems

Nowadays, with the development of technology, the production process had become more simplified and more mechanized. Tablet making is a very easy, basic, and common process.  An ideal tablet should be free of all problems and defects.  An industrial pharmacist usually encounters many of the problems at the time of manufacturing. During the production of tablet their occurs many problems out of which some could be solved, some are ignored and some needs solution to it. But for the right types of problems and solutions firstly we need to analyze the whole tableting process.

Here below are some problems that occur at the time of Production of Tablet:

1)      Sticking - Sticking is the problem that adheres to the surface of the tablet punch face, is an ongoing and costly problem.

2)      Picking - Picking is a specific type of sticking that refers to the material becoming stuck on the faces of compression tooling by its embossing design.

3)      Capping - Capping is usually found at the time of friability test, it is kind of break across the horizontal plan.

4)      Lamination – Lamination usually occurs at the time storage period, it is separated into two or more distinct shapes. 

5)      Tablet Contamination – Contamination in the tablet generally indicates itself by the black spot in the tablet.

6)      Hardness - It depends on the type of material.

7)      Cracking – Cracking generally happens due to inadequate removal of the air before and after compression.

8)      Double Impression – Double impressions is the imprinting of any design twice in the tablet at the time of compression stage.

Solutions for the Problems of Tablet production:

1)      For Sticking issue: I Holland(UK) who is a partner of Inos provides a wide range of Punches & Dies coatings on the market which is designed to meet the challenges like sticking of almost any formulation.

2)      By using I Holland’s bellows and Drip cups in conjunction with seal grove on your tablet punch will decrease the contamination in tablet production.

3)      One of the best solutions for eliminating the Capping and lamination is the type of steel you are using which will also increase overall tool life. At I Holland they have achieved exactly that with their quality PharmaGrade^® steels all of which are ESR refined at no extra cost. 

For more details visit us at Inos Technologies.

Trends of Packaging Industries and Machinery used in it

Pharmaceutical packaging is constantly advancing and in this also medicine is something that always going to be in high demand. As with most other packaged goods, pharmaceuticals need reliable and speedy packaging solutions that deliver a combination of product protection, quality, tamper evidence, patient comfort, and security needs. In the Pharmaceutical industries, three things are more important and that is accessible to the patient, Eco-friendly packaging system and ease of production while packaging.

Trends of pharmaceutical packaging are:

1)      Blister packs or cards: It is a type of preformed plastic used for the packaging of pharmaceutical products.

2)      Glass:  Glass has zero rates of interaction with chemicals in turn there is no change in product strength, aroma, and flavor.

3)      Plastics: Due to plastic packaging the product can be easily preserved, stored, transported, and stored.

4)      Foils:  It is widely used in food and pharmaceutical industries as due to foil there is a complete obstruction to light, oxygen, bacteria and moisture.

5)      Flexible Packaging:  It is a mixture of all materials and non-rigid materials.

 Machinery used in packaging

1) Blister Machine

                                 A compact and multifunctional for packaging industrial-grade blisters of solid products for medium-sized production batches, where flexibility and the simplicity of format changes are required.                  

2) Cartoner Machine

                                        It is one kind of packaging machine that forms the carton machine. It helps in forming many types of packaging like Blisters, bottles, vials, ampoules, tubes, sachets, pouches, medical technology, and cosmetics can be packed and a wide variety of plug-in and adhesive closures, as well as various designs and materials, can be processed.

3)     Track & Trace machine

                         Product in the pharmaceutical industries needs distinctive drug labeling and proof for drug identification where the roles come of track and trace machine comes. It is a very useful and essential machine for the Pharma industries.

4)     X-Ray inspection machine

                         X-ray and optical inspection machines are used for removing impurities from the product. For the accurate and uniform appearance of the product X-ray and optical inspection is very necessary. Here in the product when the high performance of the X-ray the scanner is passed then it will remove the defective pieces from the production.

For more details visit us at Inos Technologies.

What is roller compactor and its benefits?

In Today’s, Pharma industries dry granulation process is considered to be the necessary part for tablet and capsule forming. Roller Compactor plays an important role over here by converting the raw material into a fine powder. The process is conducted between two counters which are rotating the roll and presses the raw materials into a solid compact form. Roller Compactor ensures particle uniformity, increased bulk density, high yield, and environmentally friendly operation. Roller compactor is usually used in the pharmaceutical industry and also in chemical industries for fine powder formation. Basically, the roller compaction consists of three major steps: Feeding system, Compaction unit, and lastly the size decrease.

 

            

Advantages of Roller Compactor

•             Due to roller compactor their ease of process controls.

•             Roller Compactor offers a greater capacity for converting it into a fine powder.

•             Roller Compactor offers higher efficiency and it is a continuous process.

•             Roller compactor makes the dry granulation process very easy and also it is easy to operate.

•             It is used in Tablet forming, Encapsulation, Antibiotics, and Instant powder making.

•             Roller compactor is a flexible and low operational cost machine.

•             It provides the constant powder feed to the press rolls.

 

 Why use Faytec Roller Compactor?

•             Faytec is a Swiss manufacturer and their best product is Roller Compactor.

•             Faytec’s main goal is to provide the highest quality of Roller Compactor to their customers.

•             Their main aim is how to fulfill the customer's need and increase the quality of the product.

•             Faytec provides the roller compactor with all compile CGMP

•             Faytec always comes up with innovative options in roller compactor machine.

•             Faytec provides the roller compactor machine in a wide range from lab scale to the commercial part.

For more details visit us at Inos Technologies.

The Best Headspace Gas Analyzer for pharmaceutical Industries

Headspace gas Analyzer is generally the machine that is used for the measurement purpose of the gases present in the sealed packages, cans, bottles,s and many more other pharmaceutical products. Basically, the Headspace gas analyzer is equipped with a professional structure and a very highly accurate sensor. It provides us an accurate measurement of the volume and the proportion of the gases present in the products. Mainly Headspace Analysis detects Oxygen, Carbon dioxide, and even moisture control. Headspace Analyzer is available in two types Laboratory Headspace Analysis and Fully Automated Headspace Analysis. Headspace Analysis ensures the stability and sterility of the product or the package. 

       

Application:

·       It is used in the Laboratory for clinical trials.

·       Headspace Analysis can be used from stability stage to commercial stage of any industries.

·       It is used in the food and beverages industries for accurate measurement of gases present in any product.

Headspace Gas Analysis

Advantages of having Headspace Gas Analyzer

·         Headspace analysis possesses extremely compact design and superior cleanability.

·         It is applicable to vials, ampoules, cartridges, syringes and bottles.

·         Headspace Analysis for R&D, Clinical trials and many more.

·         Headspace analysis is having robust proprietary technologies.

·         It is suitable for different glass colors and types.

Why choose Xepics for Headspace Analysis?

• Xepics solutions are based on standard proprietary systems that are configured for the best matching your URS.
• Xepics is involved in the design, development, and production system of the Headspace Analysis machine.
• Xepics deliver innovations to support its customers in improving their efficiency.
• It also ensures the customer about the products which meet the worldwide guideline and regulatory standards.
• Xepics had a multidisciplinary knowledge which contributes to enhancing the business vision.

For more information visit us at Inos Technologies.

Best Machine for Packaging - Cartoner Machine

In today’s world of packaging industries, there are numerous types of products that require cartons for packaging purposes. A cartoner machine is the one whose responsibility is to make it erect, folded, and sealed cartons.  Cartons are useful for the packaging purpose of the solid and liquid dosage in pharmaceutical, chemical, and many more industries. In the Pharma industries, it is mainly used in the packaging blisters, bottles, vials, tubes, inhalers, pouches, and many more. It is also used in general packaging bottled foodstuffs, confectionery, etc., and can vary based on the scale of business. From common closing procedure to design requirements of the product all are fulfilled by the Cartoner machine. Cartoner machines are mainly used in the pharmaceutical and cosmetic industries.

Advantages of Cartoner Machine…

• Cartoner machine helps in improving the efficiency of production.
• Cartoner machine meets the requirement in process reliability, versatility and accessibility.
• The usage of cartoner machine is cost-effective.
• Cartoner machine provides high-quality standard products at a very reasonable price.
• Cartoner machine has a quick and easy format changeover.
• Cartoner machines can also be customized as per requirements.
• With the help of cartoner machine one can save time in the production process.

Why choose Ilsemann for packaging machinery?

• Ilsemann offers exclusive machinery for the packaging lines like a blister, cartoner, foil wrapping, and many more.
• It also manufactures the product range in a very innovative and customized form.
• Ilsemann’s packaging machinery is dedicated to providing a large variety of pharmaceutical products.
• Cartoner machine of Ilsemann contains higher flexibility and gives an excellent performance.
• Ilsemann’s cartoner machine is designed for a wide range of formats.
• It contains an active pre-opening mechanism.

For more information visit us at Inos Technologies.

Visual Inspection Machine for Industrial Manufacturing.

Pharmaceutical machinery must meet some basic norms in which one comes is Quality assurance. It is important to be able to depend on technology that monitors the process chain in a reliable and cost-effective manner. And for quality checking, we can be depended on one of the machines and that is the Visual Inspection machine. It is used at every place like manufacturing industrials in one or another way. Inos provides the Visual Inspection machine mainly for the vials, ampoules, and cartridges for a full range of defects.  Visual Inspection is mainly used for the detection of foreign particles and fibers. It is also used for the detection of the ampoules tip deformation, wrong shapes, and size. Visual Inspection machine is mainly used in chemical, pharmaceutical, food, and many other industries.  

Advantages of Visual Inspection Machine

·         Visual inspection machine is a cost-effective machine.

·         Due to Visual inspection machine, default items get detected and removed from the process.

·         It is easy to understand, reliable, and less time-consuming.

·         Data is recorded in the machine automatically.

·         Automatic visual inspection machine is quicker than a manual machine.

·         Visual inspection machine requires very less maintenance.

 

Why choose Xepics for Visual Inspection machine?

·         Xepics solutions are based on standard proprietary systems which are configured for best matching your URS.

·         Xepics is involved in design, development, and production system of Visual Inspection machine.

·         Xepics deliver innovations to support their customers in improving their efficiency.

·         It also ensures the customer about the products which meet the worldwide guideline and regulatory standards.

·         Xepics had a multidisciplinary knowledge which contributes to enhancing the business vision.

 For more information visit us at Inos Technologies.

Eziflow CSV Transfer System for Containment Solutions.

Thousands of powder materials which have more inertia compared to the other particles will not travel in a straight line and go with the flow which at one time may be an inhalation hazard, as being transferred in chemical and pharmaceutical industries every hour some of the materials are hazardous and harmful to the human when it comes in contact. We here at Inos look at it as our responsibility to take care of workers Safety, Sustainability, and Hygiene which can only be possible by powder transfer system like EziFlow CSV Transfer system. Due to the Eziflow CSV Transfer System, the powder form particles not come in contact with the outer environment and can be easily transferred from one process to another. Eziflow is available in multi-use and single-use formats and 4 and 6-inch bores, the Ezi-Flow CSV breaks the mold, providing superb levels of containment.  It is 4-5 times cheaper than “Old Style” Split Butterfly Valve alternatives.

 

Advantages of EziFlow CSV Transfer System

 

•             Eziflow provides the perfect solution and a unique system for the contained transfer of sensitive or hazardous products.

•             It requires very little maintenance.

•             EziFlow is user friendly and cost-effective.

•             It is available in many different sizes.

•             Worker's safety will be assured with the use of the Eziflow CSV Transfer system.

•             Hazardous products or materials can be easily transferred from one process to another.

 

Why choose Ezidock solutions for all your containment handling issues?

 

•             The Ezidock™ Systems' range of products continues to evolve to meet their customers’ needs.

•             Ezidock™ manufactures World Class products for processing, handling, and storage of semi-bulk Powders & Liquids.

•             Ezidock is always manufacturing different and innovative products and they are specialists in industrial packaging solutions for food, chemical, and pharmaceutical.

•             Ezidock’s first priority is always remained the one and only which customers demands and their problem solutions.

•             Ezidock is always trying to manufacture cost-effective products.

For more information visit us at Inos Technologies.